Camp Lemonnier is a United States Naval Expeditionary Base, situated next to Djibouti–Ambouli International Airport in Djibouti City, and home to the Combined Joint Task Force – Horn of Africa (CJTF-HOA) of the U.S. Africa Command (USAFRICOM). It is the only permanent U.S. military base in Africa. The camp is operated by U.S. Navy Region Europe, Africa, Southwest Asia; CJTF-HOA is the most notable tenant command located at the facility as of 2008.

Djibouti–Ambouli International Airport is a joint civilian/military-use airport situated in the town of Ambouli, Djibouti. It serves the national capital, Djibouti. The airport is located approximately 6 kilometres from the city centre. It occupies an area of 10 square kilometers.