The Canon EF-S 10–22mm f/3.5–4.5 USM lens is a wide to ultra-wide angle zoom lens for Canon digital single-lens reflex cameras with a Canon EF-S lens mount. The field of view has a 35 mm equivalent focal length of 16–35mm, which is analogous to the EF 16–35mm f/2.8L on a full-frame camera. The 10–22mm is an internal focusing lens. Of the 13 elements, one is of Canon's Super Ultra-Low Dispersion glass and three are aspherical elements.

The Canon EF-S lens mount is a derivative of the EF lens mount created for some Canon digital single-lens reflex cameras with APS-C sized image sensors. It was released in 2003. Cameras with the EF-S mount are backward compatible with the EF lenses and, as such, have a flange focal distance of 44.0 mm. Such cameras, however, have more clearance, allowing lens elements to be closer to the sensor than in the EF mount. Only Canon cameras released after 2003 with APS-C sized sensors support the EF-S mount.