Cape Guardafui is a headland in the autonomous Puntland region in Somalia. Coextensive with Puntland's Gardafuul administrative province, it forms the geographical apex of the Horn of Africa. Its shore at 51°27'52"E is the second easternmost point on mainland Africa after Ras Hafun. The offshore oceanic strait Guardafui Channel is named after it.

Puntland, officially the Puntland State of Somalia, is a Federal Member State in northeastern Somalia. The capital city is the city of Garoowe in the Nugal region, and its leaders declared the territory an autonomous state in 1998. Puntland had a population of 4,334,633 in 2016. Geographically to the west, Puntland lays claim to the intra-46th meridian territories that were outside European colonial rule during parts of the Scramble for Africa period.