The Capital Beltway is a beltway surrounding Harrisburg, Pennsylvania, in the United States. It is co-designated as Interstate 81 (I-81), I-83, U.S. Route 11 (US 11), US 322, and Pennsylvania Route 581 (PA 581) at various locations along the route. The beltway is primarily located in the suburbs of Harrisburg on both sides of the Susquehanna River; however, part of its southern leg passes along the southern edge of downtown. The southern section of the highway is named the Harrisburg Expressway. Officially designated in 1997, the Beltway is an assemblage of several freeways built over the preceding 45 years.

Interstate 81 (I-81) is a north–south Interstate Highway, stretching from Dandridge, Tennessee, northeast to Fisher's Landing, New York, at the Canada–United States border. In Pennsylvania, I-81 runs for 232.76 miles (374.59 km) from the Maryland state line northeast to the New York state line near Hallstead and is called the American Legion Memorial Highway. The interstate enters the state near the borough of Greencastle, serving the boroughs of Chambersburg and Carlisle, before reaching Harrisburg, the capital. After that, it climbs into the Pocono Mountains to run through the Wyoming Valley, then exits into New York. It is the longest north–south Interstate in Pennsylvania.