Captain America is a 1944 Republic black-and-white 15-chapter serial film loosely based on the Timely Comics character Captain America. It was the last Republic serial made about a superhero. It also has the distinction of being the most expensive serial that Republic ever made. It stands as the first theatrical release connected to a Marvel character; the next theatrical release featuring a Marvel hero would not occur for more than 40 years. It was the last live-action rendition of a Marvel character in any medium until Spider-Man appeared in the Spidey Super Stories segment of the children's television series The Electric Company in 1974.

Captain America is a superhero created by Joe Simon and Jack Kirby who appears in American comic books published by Marvel Comics. The character first appeared in Captain America Comics #1, published on December 20, 1940, by Timely Comics, a corporate predecessor to Marvel. Captain America's civilian identity is Steve Rogers, a frail man enhanced to the peak of human physical perfection by an experimental "super-soldier serum" after joining the United States Army to aid the country's efforts in World War II. Equipped with an American flag-inspired costume and a virtually indestructible shield, Captain America and his sidekick Bucky Barnes clashed frequently with the villainous Red Skull and other members of the Axis powers. In the final days of the war, an accident left Captain America frozen in a state of suspended animation until he was revived in modern times. He resumes his exploits as a costumed hero and becomes leader of the superhero team the Avengers, but frequently struggles as a "man out of time" to adjust to the new era.