Cass Technical High School is a magnet high school in Midtown Detroit, Michigan, United States. It was established in 1907 and is part of the Detroit Public Schools Community District. It is named after Lewis Cass.

Lewis Cass was an American military officer, politician, and statesman. He represented Michigan in the United States Senate and served in the Cabinets of two U.S. Presidents, Andrew Jackson and James Buchanan. He was also the 1848 Democratic presidential nominee. A slave owner himself, he was a leading spokesman for the doctrine of popular sovereignty, which at the time held the idea that people in each U.S state should have the right to decide on whether to permit or prohibit slavery, believing in the idea of states rights.