The Castle Donington line also known as Weston On Trent Branch Railway is a railway line in Derbyshire, England, that runs between Stenson Junction in the west and Sheet Stores Junction in the east. There are no passenger services that serve this line regularly but passenger services are occasionally routed across it. Regular passenger services are routed via Derby. The line is regularly used by freight trains and serves the East Midlands Gateway freight interchange. There are no current passenger stations on the line which previously served stations at Castle Donington and Weston-on-Trent and also linked to the Melbourne Line.

Castle Donington is a market town and civil parish in Leicestershire, England, on the edge of the National Forest and close to East Midlands Airport.