The Catawba, also known as Issa, Essa or Iswä but most commonly Iswa, are a federally recognized tribe of Native Americans, known as the Catawba Indian Nation. Their current lands are in South Carolina, on the Catawba River, near the city of Rock Hill. Their territory once extended into North Carolina, as well, and they still have legal claim to some parcels of land in that state. They were once considered one of the most powerful Southeastern tribes in the Carolina Piedmont, as well as one of the most powerful tribes in the South as a whole, with other, smaller tribes merging into the Catawba as their post-contact numbers dwindled due to the effects of colonization on the region.

North Carolina is a state in the Southeastern region of the United States. It is bordered by Virginia to the north, the Atlantic Ocean to the east, South Carolina to the south, Georgia to the southwest, and Tennessee to the west. The state is the 28th-largest and 9th-most populous of the United States. Along with South Carolina, it makes up the Carolinas region of the East Coast. At the 2020 census, the state had a population of 10,439,388. Raleigh is the state's capital and Charlotte is its most populous city. The Charlotte metropolitan area, with an estimated population of 2,805,115 in 2023, is the most populous metropolitan area in North Carolina, the 22nd-most populous in the United States, and the largest banking center in the nation after New York City. The Research Triangle, with an estimated population of 2,368,947 in 2023, is the second-most populous combined metropolitan area in the state, 31st-most populous in the United States, and is home to the largest research park in the United States, Research Triangle Park.