Catholic resistance to Nazi Germany was a component of German resistance to Nazism and of Resistance during World War II. The role of the Catholic Church during the Nazi years remains a matter of much contention. From the outset of Nazi rule in 1933, issues emerged which brought the church into conflict with the regime and persecution of the church led Pope Pius XI to denounce the policies of the Nazi Government in the 1937 papal encyclical Mit brennender Sorge. His successor Pius XII faced the war years and provided intelligence to the Allies. Catholics fought on both sides in World War II and neither the Catholic nor Protestant churches as institutions were prepared to openly oppose the Nazi State.

The Roman Catholic Church suffered persecution in Nazi Germany. The Nazis claimed jurisdiction over all collective and social activity. Clergy were watched closely, and frequently denounced, arrested and sent to Nazi concentration camps. Welfare institutions were interfered with or transferred to state control. Catholic schools, press, trade unions, political parties and youth leagues were eradicated. Anti-Catholic propaganda and "morality" trials were staged. Monasteries and convents were targeted for expropriation. Prominent Catholic lay leaders were murdered, and thousands of Catholic activists were arrested.