Catherine Cavadini is an American voice actress. She is most well known as the original voice of Blossom on Cartoon Network's short series What a Cartoon! and the animated television series The Powerpuff Girls, and as Tanya Mousekewitz in An American Tail: Fievel Goes West.

The Powerpuff Girls is an American superhero animated television series created by animator Craig McCracken and produced by Hanna-Barbera for Cartoon Network. The show centers on Blossom, Bubbles, and Buttercup, three kindergarten-aged girls with superpowers. They live in the fictional city of Townsville with their father and creator, a scientist named Professor Utonium, and are frequently called upon by the city's mayor to help fight nearby criminals and other enemies using their powers.