Cayo Hueso is a consejo popular (ward) in the municipality of Centro Habana, Havana, Cuba. A traditionally working-class neighborhood populated by Afro-Cubans, it is known for its many cultural landmarks such as the Callejón de Hamel, the Fragua Martiana Museum and the Parque de los Mártires Universitarios.

Centro Habana is one of the 15 municipalities or boroughs in the city of Havana, Cuba. There are many retail spaces (such as Plaza de Carlos III commercial center, office buildings, hotels, bars and clubs. A chinatown - Barrio Chino - is also located in this district. It is a smaller municipality of Havana, and it has the highest population density.