Cebu City's 2nd congressional district is one of the two congressional districts of the Philippines in the city of Cebu. It has been represented in the House of Representatives of the Philippines since 1987. The district consists of thirty four barangays of the city locally referred to as the "South District". It is currently represented in the 19th Congress by Eduardo Rama Jr. of the Lakas–CMD.

Tomas dela Rama Osmeña, known as Tommy Osmeña, is a Filipino politician who served as the Mayor of Cebu City thrice: first from 1987 to 1995, again from 2001 to 2010, and lastly from 2016 to 2019. He also served as Congressman representing the second district of Cebu City from 2010 to 2013. He is a grandson of former Philippine President Sergio Osmeña.