Panama's Centennial Bridge is a major bridge crossing the Panama Canal. It was built to supplement the overcrowded Bridge of the Americas and to replace it as the carrier of the Pan-American Highway. Upon its opening in 2004, it became the second permanent crossing of the canal.

The Bridge of the Americas is a road bridge in Panama which spans the Pacific entrance to the Panama Canal. Designed by Sverdrup & Parcel, it was completed in 1962 at a cost of US$20 million, connecting the north and south American land masses, connecting the American Continent. Two other bridges cross the canal: the Atlantic Bridge at the Gatun locks and the Centennial Bridge.