Central is a census-designated place (CDP) in Yukon-Koyukuk Census Area, Alaska, United States. At the 2010 census the population was 96, down from 134 in 2000. Every February, Central hosts a checkpoint for the long-distance Yukon Quest sled dog race.

Yukon–Koyukuk Census Area is a census area in the U.S. state of Alaska. As of the 2020 census, the population was 5,343, down from 5,588 in 2010. With an area of 147,842.51 sq mi (382,910.3 km2), it is the largest of any county or county-equivalent in the United States, or slightly larger than the entire state of Montana. It is part of the unorganized borough of Alaska and therefore has no borough seat. Its largest communities are the cities of Galena, in the west, and Fort Yukon, in the northeast.