The Central Oregon & Pacific Railroad is a Class II railroad operating between Northern California and Eugene, Oregon, United States. It was previously a mainline owned by the Southern Pacific Railroad (SP) between Eugene and Weed, California via Medford, Oregon. SP sold the route on December 31, 1994, in favor of using its route to Eugene via Klamath Falls, Oregon and Cascade Summit.
An EMD GP38-2 leads an NRHS excursion over the Coos Bay Line in 2005.