The Central Park North–110th Street station is a station on the IRT Lenox Avenue Line of the New York City Subway, located at the intersection of 110th Street and Lenox Avenue at the southern edge of Harlem, Manhattan. It is served by the 2 and 3 trains at all times.

110th Street is a street in the New York City borough of Manhattan. It is commonly known as the boundary between Harlem and Central Park, along which it is known as Central Park North. In the west, between Central Park West/Frederick Douglass Boulevard and Riverside Drive, it is co-signed as Cathedral Parkway.