The Central United States is sometimes conceived as between the Eastern and Western as part of a three-region model, roughly coincident with the U.S. Census's definition of the Midwestern United States plus the western and central portions of the U.S. Census's definition of the Southern United States. The Central States are typically considered to consist of North Dakota, South Dakota, Nebraska, Kansas, Oklahoma, Texas, Minnesota, Iowa, Missouri, Arkansas, Louisiana, Wisconsin, Illinois, Michigan, Indiana, Ohio, Kentucky, Tennessee, West Virginia, Mississippi and Alabama.

Topeka is the capital city of the U.S. state of Kansas and the seat of Shawnee County. It is along the Kansas River in the central part of Shawnee County, in northeast Kansas, in the Central United States. As of the 2020 census, the population of the city was 126,587. The Topeka metropolitan statistical area, which includes Shawnee, Jackson, Jefferson, Osage, and Wabaunsee Counties, had a population of 233,870 in the 2010 census.