Centruroides is a genus of scorpions of the family Buthidae. Several North American species are known by the common vernacular name bark scorpion. Numerous species are extensively found throughout the southern United States, Mexico, Central America, the Antilles and northern South America. Some are known for their interesting patterning or large size ; most if not all fluoresce strongly under ultraviolet illumination, except after moulting. They contain several highly venomous species, and fatalities are known to occur. The venom of the Mexican scorpion Centruroides limpidus limpidus contains the neurotoxins Cll1 and Cll2.

Scorpions are predatory arachnids of the order Scorpiones. They have eight legs and are easily recognized by a pair of grasping pincers and a narrow, segmented tail, often carried in a characteristic forward curve over the back and always ending with a stinger. The evolutionary history of scorpions goes back 435 million years. They mainly live in deserts but have adapted to a wide range of environmental conditions, and can be found on all continents except Antarctica. There are over 2,500 described species, with 22 extant (living) families recognized to date. Their taxonomy is being revised to account for 21st-century genomic studies.