Châteauneuf-du-Pape is a commune in the Vaucluse department in the Provence-Alpes-Côte d'Azur region in Southeastern France. The village lies about 3 kilometres (1.9 mi) to the east of the Rhône and 12 kilometres (7.5 mi) north of the town of Avignon.

The Rhône is a major river in France and Switzerland, rising in the Alps and flowing west and south through Lake Geneva and southeastern France before discharging into the Mediterranean Sea. At Arles, near its mouth, the river divides into the Great Rhône and the Little Rhône. The resulting delta forms the Camargue region.