The Chapel of the Holy Cross is a Roman Catholic chapel built from 1954 to 1956 into the red rock buttes of Sedona, Arizona, within the Coconino National Forest. It was inspired and commissioned by local rancher and sculptor Marguerite Brunswig Staude, and was designed by August K. Strotz of the firm of Anshen & Allen, with Richard Hein of the firm as the project architect. The chapel is under the auspices of the episcopal see of the Roman Catholic Diocese of Phoenix and its ministry is conducted by St. John Vianney Parish, Sedona.

The Diocese of Phoenix is a Latin Church ecclesiastical territory, or diocese, in western and central Arizona in the United States. It is a suffragan diocese of the ecclesiastical province of the Archdiocese of Santa Fe.