Charles Anthony Rodríguez-Colón is a New York City-born Puerto Rican politician affiliated with the New Progressive Party (NPP). He served as the eleventh president of the Senate of Puerto Rico from 1997 until 2000.

The Senate of Puerto Rico is the upper house of the Legislative Assembly of Puerto Rico, the territorial legislature of Puerto Rico. The Senate, together with the House of Representatives of Puerto Rico, control the legislative branch of the government of Puerto Rico.