Chase City is a town in Mecklenburg County, Virginia, United States. Chase City was incorporated in 1873 and named for Salmon P. Chase, United States Chief Justice and Lincoln's Secretary of the Treasury. The population was 2,053 at the 2020 census. Tobacco and other crops are grown nearby.

Mecklenburg County is a county in the Commonwealth of Virginia. As of the 2020 census, the population was 30,319. Its county seat is Boydton.