The Compagnie des chemins de fer du Midi, also known in English as the Midi or Southern Railway, was an early French railway company which operated a network of routes in the southwest of the country, chiefly in the area between its main line – which ran from Bordeaux, close to the Atlantic coast, to Sète on the Mediterranean – and the Pyrenees.

Émile Pereire and his brother Isaac Pereire were major figures in the development of France's finance and infrastructure during the Second French Empire. The Pereire brothers challenged the dominance of the Rothschilds in continental European finance, known at the time as haute finance. Their attempt was temporarily successful, and even though it collapsed in the late 1860s, it contributed to a more developed and vibrant economic landscape. Like the Rothschilds, the Pereires were Jews, but unlike them, they were Sephardi of Portuguese origin.