Chesterfield County is a county located in the U.S. state of South Carolina. As of the 2020 census, its population was 43,273. Its county seat is Chesterfield. The largest community in the county is Cheraw. It is located north of the Midlands, in the Pee Dee region, on its border with North Carolina.

Cheraw is a town on the Pee Dee River in Chesterfield County, South Carolina, United States. The population was 5,040 at the 2020 census. The greater Cheraw area in the zip code 29520 has a population of 13,689 according to the 2019 ACS data. It has been nicknamed "The Prettiest Town in Dixie".