The Chigi Chapel or Chapel of the Madonna of Loreto is the second chapel on the left-hand side of the nave in the Basilica of Santa Maria del Popolo in Rome. It is the only religious building of Raphael which has been preserved in its near original form. The chapel is a treasure trove of Italian Renaissance and Baroque art and is ranked among the most important monuments in the basilica.

A chapel is a Christian place of prayer and worship that is usually relatively small. The term has several meanings. First, smaller spaces inside a church that have their own altar are often called chapels; the Lady chapel is a common type of these. Second, a chapel is a place of worship, sometimes interfaith, that is part of a building, complex, or vessel with some other main purpose, such as a school, college, hospital, palace or large aristocratic house, castle, barracks, prison, funeral home, cemetery, airport, or a military or commercial ship. Third, chapels are small places of worship, built as satellite sites by a church or monastery, for example in remote areas; these are often called a chapel of ease. A feature of all these types is that often no clergy were permanently resident or specifically attached to the chapel.