Chomutov District is a district in the Ústí nad Labem Region of the Czech Republic. Its capital is the city of Chomutov.

Ústí nad Labem Region or Ústecký Region is an administrative unit of the Czech Republic, located in the north-western part of the historical land of Bohemia, and named after the capital, Ústí nad Labem. It covers the majority of the former North Bohemia province and is part of the broader area of North Bohemia.