Chondrocyte
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Chondrocytes are the only cells found in healthy cartilage. They produce and maintain the cartilaginous matrix, which consists mainly of collagen and proteoglycans. Although the word chondroblast is c
Light micrograph of undecalcified hyaline cartilage showing its chondrocytes and organelles, lacunae and matrix
Chondrocytes in hyaline cartilage
Endochondral ossification
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Endochondral ossification is one of the two essential pathways by which bone tissue is produced during fetal development and bone repair of the mammalian skeletal system, the other pathway being intra
Chondrocyte
…embryo which may result in limb malformations. Chondrocytes undergo terminal differentiation when they become hypertrophic, which happens during endochondral ossification. This last stage is characterized by major phenotypic changes in the cell. The chondrocyte in cartilage matrix has rounded or polygonal structure. The…
A schematic representation of endochondral ossification.
A schematic for long bone endochondral ossification.
Zones of endochondral ossification.