Christian Brothers Academy (CBA) is a private Catholic college preparatory school in suburban Syracuse, New York run by the Brothers of the Christian Schools, founded by St. John Baptist de La Salle. Located within the Roman Catholic Diocese of Syracuse, the school has more than 750 students in grades seven through twelve. It was founded in 1900 by the Christian Brothers, who still run the school, though most of the teachers are laity. In 1960, it moved from its original site on Willow Street in downtown Syracuse to its current location in suburban Dewitt on Randall Road. CBA was a boys-only school until September 1987. CBA opened to girls after Syracuse's all-girls school, The Franciscan Academy, closed and many of those parents actively lobbied to have CBA accept female students.

DeWitt is a town in Onondaga County, New York, United States. As of the 2020 census, the population was 26,074. The town is named after major Moses DeWitt, a judge and soldier. An eastern suburb of Syracuse, DeWitt also is the site of most of the campus and all of the academic buildings of Le Moyne College.