Christian County is a county located in the U.S. state of Kentucky. As of the 2020 census, the population was 72,748. Its county seat is Hopkinsville. The county was formed in 1797. Christian County is part of the Clarksville, Tennessee–Kentucky Metropolitan Statistical Area.

Hopkinsville is a home rule-class city in and the county seat of Christian County, Kentucky, United States. The population at the 2020 census was 31,180.