Christmas Eve

Christmas Eve is the evening or entire day before Christmas Day, the festival commemorating the birth of Jesus. Christmas Day is observed around the world, Christmas Eve is observed as a full or partial holiday in anticipation of Christmas Day. Together, both days are considered one of the most culturally significant celebrations in Christendom and Western society. Christmas celebrations in the denominations of Western Christianity have long begun on Christmas Eve, due in part to the Christian liturgical day starting at sunset, a practice inherited from Jewish tradition and based on the story of Creation in the Book of Genesis: "And there was evening, there was morning – the first day." Many churches still ring their church bells and hold prayers in the evening. Since tradition holds that Jesus was born at night, Midnight Mass is celebrated on Christmas Eve, traditionally at midnight, in commemoration of his birth; the idea of Jesus being born at night is reflected in the fact that Christmas Eve is referred to as Heilige Nacht in German, Nochebuena in Spanish and in other expressions of Christmas spirituality, such as the song "Silent Night, Holy Night".

Many other varying cultural traditions and experiences are associated with Christmas Eve around the world, including the gathering of family and friends, the singing of Christmas carols, the illumination and enjoyment of Christmas lights and other decorations, the wrapping and opening of gifts, general preparation for Christmas Day. Legendary Christmas gift-bearing figures including Santa Claus, Father Christmas and Saint Nicholas are often said to depart for their annual journey to deliver presents to children around the world on Christmas Eve, although until the Protestant introduction of Christkind in 16th-century Europe, such figures were said to instead deliver presents on the eve of Saint Nicholas' feast day. Roman Catholics and high church Anglicans traditionally celebrate Midnight Mass, which begins either at or sometime before midnight on Christmas Eve; this ceremony, held in churches throughout the world, celebrates the birth of Christ, believed to have occurred at night. Midnight Mass is popular in Lithuania.

In recent years some churches have scheduled their "Midnight" Mass as early as 7 pm. This better suits the young children, whose choral singing has become a popular feature in some traditions. In Spanish-speaking areas, the Midnight Mass is sometimes referred to as Misa de Gallo, or Missa do Galo in Portuguese. In the Philippines, the custom has expanded into the nine-day Simbang Gabi, when Filipinos attend dawn Masses from 16 December, continuing daily until Christmas Eve. In 2009 Vatican officials scheduled the Midnight Mass to start at 10 pm so that the 82-year-old Pope Benedict XVI would not have too late a night. A nativity scene may be erected indoors or outdoors, is composed of figurines depicting the infant Jesus resting in a manger and Joseph. Other figures in the scene may include angels and various animals; the figures may be made of any material, arranged in a stable or grotto. The Magi may appear, are sometimes not placed in the scene until the week following Christmas to account for their travel time to Bethlehem.

While most home nativity scenes are packed away at Christmas or shortly thereafter, nativity scenes in churches remain on display until the feast of the Baptism of the Lord. Whilst it does not include any kind of Mass, the Church of Scotland has a service beginning just before midnight, in which carols are sung; the Church of Scotland no longer holds Hogmanay services on New Year's Eve, however. The Christmas Eve Services are still popular. On Christmas Eve, the Christ Candle in the center of the Advent wreath is traditionally lit in many church services. In candlelight services, while singing Silent Night, each member of the congregation receives a candle and passes along their flame, first received from the Christ Candle. Lutherans traditionally practice Christmas Eve Eucharistic traditions typical of Germany and Scandinavia. "Krippenspiele", special festive music for organ and brass choirs and candlelight services make Christmas Eve one of the highlights in the Lutheran Church calendar. Christmas Vespers are popular in the early evening, midnight services are widespread in regions which are predominantly Lutheran.

The old Lutheran tradition of a Christmas Vigil in the early morning hours of Christmas Day can still be found in some regions. In eastern and middle Germany, congregations still continue the tradition of "Quempas singing": separate groups dispersed in various parts of the church sing verses of the song "He whom shepherds once came Praising" responsively. Methodists celebrate the evening in different ways. Some, in the early evening, come to their church to celebrate Holy Communion with their families; the mood is solemn, the only visible light is the Advent Wreath, the candles upon the Lord's Table. Others celebrate the evening with services of light, which include singing the song Silent Night as a variety of candles are lit. Other churches have late evening services at 11 pm, so that the church can celebrate Christmas Day together with the ringing of bells at midnight. Others offer Christmas Day services as well; the annual "Nine Lessons and Carols", broadcast from King's College, Cambridge on Christmas Eve, has established itself a Christmas custom in the United Kingdom.

It is broadcast outside the UK

Srebrna krila

Srebrna krila are a Croatian pop band from Zagreb that are popular across the ex-Yugoslav states. The band was created with Vlado Kalember as the lead singer. Most of their Kalember-era hits were written by Đorđe Novković. In 1988 the band represented Yugoslavia at the Eurovision Song Contest with the song "Mangup", placing at number 6. Throughout the 1980s and 1990s the band went through a series of different incarnations. Kalember left the band after their 1986 album 30 u hladu; the band disappeared for several years after the death of its leader Muc in 2000. Srebrna krila reunited 1.6. 2012. At Zagreb Bundek and announced the return to the scene. At the end of August 2012 they announced a new comeback album called "Srebrna Krila 2012". Vlado Kalember: vocals, bass guitar Dado Jelavić: guitars Adi Karaselimović: drums Duško Mandić: guitars Mustafa "Muc" Ismailovski: keyboards Slavko Pintarić Pišta: drums Lidija Asanović: vocals Oleg Colnago: bass guitar Vlatka Pokos: vocals Vlatka Grakalić: vocals Barbara Vujević: vocals Daniel Popović: guitars Minea: vocals Srebrna Krila Ja sam samo jedan od mnogih sa gitarom Sreo sam ljubav iz prve pjesme Ša-la-la Julija i Romeo Zadnja ploča Silverwings Ćao amore Djevuška Uspomene Nek' živi ljubav – za djecu 30 u hladu Mangup Poleti golubice Zašto nisam miljenica sudbine Ljubi me noćas Ljubav je za ljude sve O kako ludo se osjećam Tamo gdje ljubav stanuje Nebo vidi, nebo zna Mega hitova Srebrnih krila Zlatna kolekcija Platinum Collection Srebrna krila 2012 Srebrna krila at Croatia Records THE PLATINUM COLLECTION SREBRNA KRILA, INTERVJU

CYP17A1 inhibitor

A CYP17A1 inhibitor is a type of drug which inhibits the enzyme CYP17A1. It may inhibit both of the functions of the enzyme, 17α-hydroxylase and 17,20-lyase, or may be selective for inhibition of one of these two functions; these drugs prevent the conversion of pregnane steroids into androgens like testosterone and therefore are androgen biosynthesis inhibitors and functional antiandrogens. Examples of CYP17A1 inhibitors include the older drug ketoconazole and the newer drugs abiraterone acetate, orteronel and seviteronel; the CYP17A1 inhibitors that have been marketed, like abiraterone acetate, are used in the treatment of prostate cancer. CYP17A1 inhibitors that are not selective for inhibition of 17,20-lyase must be combined with a glucocorticoid such as prednisone in order to avoid adrenal insufficiency and mineralocorticoid excess caused by prevention of cortisol production. Steroidogenic enzyme Steroidogenesis inhibitor Nonsteroidal antiandrogen Gonadotropin-releasing hormone analogue