Church Hill is a small unincorporated community in Jefferson County, Mississippi, United States. It is located eight miles east of the Mississippi River and approximately 18 miles north of Natchez at the intersection of highway 553 and Church Hill Road. Church Hill was a community of wealthy cotton planters and enslaved people before the American Civil War. Soil erosion, which had been going on since well before the Civil War, caused the area to decline into a poor farming community with none of the land under cultivation by 1999. The area is remarkable because its antebellum buildings are mostly intact with few modern buildings having been built.

Jefferson County is a county located in the U.S. state of Mississippi; its western border is formed by the Mississippi River. As of the 2020 census, the population was 7,260, making it the fourth-least populous county in Mississippi. Its first county seat was located at Old Greenville until 1825, which no longer exists, before moving to Fayette. The county is named for U.S. President Thomas Jefferson.