The Church of the Assumption is a Roman Catholic church within George Town in the Malaysian state of Penang. Established following the founding of George Town in 1786, it is the third oldest Catholic church in Malaysia. The church was also the seat of the bishop of Penang from 1955 to 2003.

The Roman Catholic Diocese of Penang is situated in the northern as well as the east coast region of Peninsular Malaysia covering 4 northern states, namely Perlis, Kedah, Penang and Perak as well as the east coast state of Kelantan. It was created on 25 February 1955 together with the Archdiocese of Kuala Lumpur. It is under the ecclesiastical province of Kuala Lumpur.