Cimarron County is the westernmost county in the U.S. state of Oklahoma. Its county seat is Boise City. As of the 2020 census, its population was 2,296, making it the least-populous county in Oklahoma; and indeed, throughout most of its history, it has had both the smallest population and the lowest population density of any county in Oklahoma. Located in the Oklahoma Panhandle, Cimarron County contains the only community in the state (Kenton) that observes the Mountain Time Zone. Black Mesa, the highest point in the state, is in the northwest corner of the county. The Cimarron County community of Regnier has the distinction of being the driest spot in Oklahoma ranked by lowest annual average precipitation, at just 15.62 inches; at the same time, Boise City is the snowiest location in Oklahoma ranked by highest annual average snowfall, at 31.6 inches.

The Dust Bowl was the result of a period of severe dust storms that greatly damaged the ecology and agriculture of the American and Canadian prairies during the 1930s. The phenomenon was caused by a combination of natural factors and human-made factors: a failure to apply dryland farming methods to prevent wind erosion, most notably the destruction of the natural topsoil by settlers in the region. The drought came in three waves: 1934, 1936, and 1939–1940, but some regions of the High Plains experienced drought conditions for as long as eight years.