The City of San Luis Obispo Historic Resources consists of buildings and sites designated by the City of San Luis Obispo, California, as historic resources.

The Motel Inn, located in San Luis Obispo, California, United States, was the first "motel" in the world, and the origin of that word, from "Mo-Tel", which is a play on the word "hotel" by combining the words "motor hotel". It opened on December 12, 1925, and closed in 1991. The Apple Farm Inn, located next door, is expanding and incorporating parts of the original hotel that are still standing into additional rooms.