Ciudad del Este is the second-largest city in Paraguay and capital of the Alto Paraná Department, situated on the Paraná River. It is located 327 km east of Asunción, the capital, and is adjacent to the border with Brazil, to which it is connected by the Friendship Bridge on the Paraná River. It is the largest city within the Triple Frontier region, which borders Foz do Iguaçu, Brazil and Puerto Iguazú, Argentina. The Itaipú Dam, one of the largest hydroelectric power plants in the world, is near Ciudad del Este, as is the Iguazu Falls.

Alto Paraná is a department in Paraguay. The capital is Ciudad del Este.