Claude of France was the ruling Duchess of Brittany from 1514 until her death in 1524 and Queen of France by marriage to King Francis I, which was also in 1514, shortly before he became king on the death of her father. She was a daughter of King Louis XII of France and his second wife, the duchess regnant Anne of Brittany.

Marguerite de Navarre, also known as Marguerite of Angoulême and Margaret of Navarre, was a princess of France, Duchess of Alençon and Berry, and Queen of Navarre by her second marriage to King Henry II of Navarre. Her brother became King of France, as Francis I, and the two siblings were responsible for the celebrated intellectual and cultural court and salons of their day in France. Marguerite is the ancestress of the Bourbon kings of France, being the mother of Jeanne d'Albret, whose son, Henry of Navarre, succeeded as Henry IV of France, the first Bourbon king. As an author and a patron of humanists and reformers, she was an outstanding figure of the French Renaissance. Samuel Putnam called her "The First Modern Woman".