Clay Daniel Buchholz is an American former professional baseball pitcher. He played in Major League Baseball (MLB) for the Boston Red Sox, Philadelphia Phillies, Arizona Diamondbacks, and Toronto Blue Jays. Buchholz made his MLB debut with the Red Sox in 2007. In his second major league start, he pitched a no-hitter, becoming the third MLB pitcher since 1900 to throw a no-hitter in his first or second start and the first Red Sox rookie to throw one. He was a two-time MLB All-Star.

In baseball, a no-hitter or no-hit game is a game in which a team does not record a hit through conventional methods. Major League Baseball (MLB) officially defines a no-hitter as a completed game in which a team that batted in at least nine complete innings recorded no hits. A pitcher who prevents the opposing team from achieving a hit is thereby said to have "thrown a no-hitter". In most cases, no-hitters are recorded by a single pitcher who throws a complete game; one thrown by two or more pitchers is a combined no-hitter.