Clay Cross is a town and a civil parish in the North East Derbyshire district of Derbyshire, England. It is a former industrial and mining town, about 5 miles (8.0 km) south of Chesterfield. It is directly on the A61. Surrounding settlements include North Wingfield, Tupton, Pilsley and Ashover.

North East Derbyshire is a local government district in Derbyshire, England. The council is based in the large village of Wingerworth. The district also includes the towns of Dronfield and Clay Cross as well as numerous villages and surrounding rural areas.