Clayoquot Sound is located on the west coast of Vancouver Island in the Canadian province of British Columbia. It is bordered by the Esowista Peninsula to the south, and the Hesquiaht Peninsula to the North. It is a body of water with many inlets and islands. Major inlets include Sydney Inlet, Shelter Inlet, Herbert Inlet, Bedwell Inlet, Lemmens Inlet, and Tofino Inlet. Major islands include Flores Island, Vargas Island, and Meares Island. The name is also used for the larger region of land around the waterbody.

Meares Island is one of the many islands surrounding the Village of Tofino, British Columbia, Canada. Its name was given in 1862 by George Henry Richards, captain of HMS Hecate, in honor of John Meares. The island is located in the Clayoquot Sound region and is the location of Opitsat, the main village of the Tla-o-qui-aht First Nations, and was the location of Fort Defiance, a short-lived American fur-trading post founded by Captain Robert Gray.