Cleopatra 2525 is an American science fiction television series that aired in syndication for two seasons, from January 2000 to March 2001. Produced by Renaissance Pictures and distributed by Studios USA, many stations aired it as part of the Back2Back Action Hour, along with Jack of All Trades.

Jack of All Trades is a half-hour-long syndicated action comedy TV series which ran for two seasons in 2000. With Cleopatra 2525, it formed the Back2Back Action Hour and both shows were notable for being the first American non-animated action series to be produced in the half-hour format since the 1970s. The show was canceled in the middle of its second season.