Clinton Square is an intersection in downtown Syracuse, New York, United States. The square was the original town center and first came into existence in the early 19th century where roadways from north and south convened. With the opening of the Erie Canal in 1825 the intersection was further transformed. During the 19th century, the square was a marketplace that also hosted several public events, including an 1870 public barbecue reportedly attended by 20,000 people.

The Jerry Rescue occurred on October 1, 1851, and involved the public rescue of a fugitive slave who had been arrested the same day in Syracuse, New York, during the anti-slavery Liberty Party's state convention. The escaped slave was William Henry, a 40-year-old cooper from Missouri whose slave name was "Jerry."