The Clutha River is the second longest river in New Zealand and the longest in the South Island. It flows south-southeast 338 kilometres (210 mi) through Central and South Otago from Lake Wānaka in the Southern Alps to the Pacific Ocean, 75 kilometres (47 mi) south west of Dunedin. It is the highest volume river in New Zealand, and the swiftest, with a catchment of 21,000 square kilometres (8,100 sq mi), discharging a mean flow of 614 cubic metres per second (21,700 cu ft/s). The river is known for its scenery, gold-rush history, and swift turquoise waters. A river conservation group, the Clutha Mata-Au River Parkway Group, is working to establish a regional river parkway, with a trail, along the entire river corridor.

South Otago lies in the south east of the South Island of New Zealand. As the name suggests, it forms the southernmost part of the geographical region of Otago.