Coast Guard Air Station San Francisco is a United States Coast Guard Air Station located 13 miles (21 km) south of downtown San Francisco, California, at the San Francisco International Airport in an unincorporated area of San Mateo County. The air station sits adjacent to the airport which consists of its own ramp, one hangar, an administration building and several other support structures.

A Coast Guard Air Station provides aviation support for the United States Coast Guard. The Coast Guard operates approximately 210 aircraft from 24 Coast Guard Air Stations in the United States. Fixed-wing aircraft, such as the HC-130 Hercules, are built for long range missions and operate from air stations. The MH-65D Dolphin and Sikorsky HH-60 Jayhawk helicopters also operate from Air Stations, Air Facilities and flight deck equipped cutters.