Coatesville station is an Amtrak intercity rail station located in Coatesville, Pennsylvania. It is served by most Amtrak Keystone Service trains. The station has two side platforms serving the outer tracks of the three-track Philadelphia to Harrisburg Main Line.

Coatesville is a city in Chester County, Pennsylvania, United States. The population was 13,350 at the 2020 census. Coatesville is approximately 39 miles west of Philadelphia. It developed along the Philadelphia and Lancaster Turnpike beginning in the late 18th century. It spans U.S. Route 30, the "Main Line" highway that runs west of Philadelphia.