Coffee County is a county located in the southeastern part of the U.S. state of Alabama. As of the 2020 census, the population was 53,465. Its name is in honor of General John Coffee.

John R. Coffee was an American planter of English descent, and a state militia brigadier general in Tennessee. He commanded troops under General Andrew Jackson during the Creek Wars (1813–14) and during the Battle of New Orleans in the War of 1812.