Cohuna is a town situated 274 kilometres (170 mi) north of Melbourne, on the Murray Valley Highway, in northern Victoria, Australia. At the 2016 census, Cohuna had a population of 2,415.

Murray Valley Highway is a 663-kilometre (412 mi) state highway located in Victoria and New South Wales, Australia. The popular tourist route mostly follows the southern bank of the Murray River and effectively acts as the northernmost highway in Victoria. For all but the western end's last three kilometres, the highway is allocated route B400.