The Coke Zero Sugar 400 is an annual NASCAR Cup Series stock car race at Daytona International Speedway. First held in 1959, the event consists of 160 laps, 400-mile (640 km), and is the second of two major stock car events held at Daytona on the Cup Series circuit, the other being the Daytona 500. From its inception in 1959 through 2019, it was traditionally held on or around the United States' Independence Day. In 1998, it became the first stock car race at Daytona to be held at night under-the-lights. In 2020, the race was moved to late August.

Daytona International Speedway is a race track in Daytona Beach, Florida, United States, about 50 mi (80 km) north of Orlando. Since opening in 1959, it has been the home of the Daytona 500, the most prestigious race in NASCAR as well as its season opening event. The venue also hosts the 24 Hours of Daytona, the most prestigious IMSA race and one of the three events that make up the Triple Crown of endurance racing. In addition to NASCAR and IMSA, the track also hosts races of ARCA, AMA Superbike, SCCA, and AMA Supercross. The track features multiple layouts including the primary 2.500 mi (4.023 km) high-speed tri-oval, a 3.560 mi (5.729 km) sports car course, a 2.950 mi (4.748 km) motorcycle course, and a 1,320 ft (400 m) karting and motorcycle flat-track. The track's 180-acre (73 ha) infield includes the 29-acre (12 ha) Lake Lloyd, which has hosted powerboat racing.