Colón Island is the northernmost and main island in the Bocas del Toro Archipelago located in Bocas del Toro Province, Panama. The capital city of the province, Bocas del Toro, is located on the island and is one of Panama's main tourist attractions with over 150,000 visitors per year and an 8% annual rate of growth in tourism.

Bocas del Toro (Spanish pronunciation: [ˈbokas ðel ˈtoɾo]; meaning "Mouths of the Bull") is a province of Panama. Its area is 4,643.9 square kilometers, comprising the mainland and nine main islands. The province consists of the Bocas del Toro Archipelago, Bahía Almirante, Chiriquí Lagoon, and adjacent mainland. The capital is the city of Bocas del Toro on Isla Colón. Other major cities or towns include Almirante and Changuinola. The province has a population of 159,228 as of 2023.