College Avenue is the oldest campus of Rutgers University – New Brunswick, in New Brunswick, New Jersey, U.S. It includes the historic seat of the university, known as Old Queens and the campus of the New Brunswick Theological Seminary. Many classes are taught in the Voorhees Mall area, also home to the Zimmerli Art Museum. It is within walking distance of the train, shops, restaurants, and theaters in downtown New Brunswick and is served by Rutgers Campus Buses, a zero-fare bus network.

Rutgers University–New Brunswick is one of three regional campuses of Rutgers University, a public land-grant research university consisting of four campuses in New Jersey. It is located in New Brunswick and Piscataway. It is the oldest campus of the university, the others being in Camden and Newark. The campus is composed of several smaller campuses that are large distances away from each other: College Avenue, Busch, Livingston, Cook, and Douglass, the latter two sometimes referred to as "Cook/Douglass", as they are adjacent to each other. All 4 subcampuses connect primarily via State Route 18. Rutgers–New Brunswick also includes several buildings in downtown New Brunswick. It is classified among "R1: Doctoral Universities – Very high research activity". The New Brunswick campuses include 19 undergraduate, graduate, and professional schools. The New Brunswick campus is also known as the birthplace of college football.