Club Social y Deportivo Colo-Colo is a Chilean professional football club based in Macul, Santiago. Founded in 1925 by David Arellano, it competes in the Chilean Primera División, from which the club has never been relegated. The team has played its home games at Estadio Monumental David Arellano since 1989. Colo-Colo is regarded as the most successful club in Chilean football.

Macul is a commune of Chile located in the central-eastern part of the Greater Santiago area, bordered by the communes of Ñuñoa to the north, San Joaquín to the west, Peñalolén to the east and La Florida to the south.